Nvidia AND AMD drivers on same installation?

[methanoid]

I'd like to use the same VM image (KVM passthrough of GPU) for two different GPUs, one Nvidia (old K2000 Kepler Quadro) and one AMD (RX6800). Can I do that? Is it gonna confuse the heck if I boot swapping GPUs or do I need separate VM images for each GPU?

Any gotchas I need to know about please?

[Schwarzer Kater]

You can only passthrough one GPU if one is already used for your host system - either the Nvidia or the AMD.
What is your host system?
Is it a VM image with Kubuntu 23.04?

AMD (open source) drivers are always there in Kubuntu and do nothing if you start a system with an NVidia graphics card and additional NVidia drivers.
On the other hand I have experienced problems several times (but not always and on physical hardware) when I started Linux systems with NVidia drivers installed (and no NVidia card) but the graphics card was AMD.
You will have to try for yourself.